Alternative Treatments: Stem Cell Treatments


Stem Cell Treatments have been making headlines for years. From controversy to life saving treatment, they have certainly made waves. But how can stem cells be applied to Multiple Sclerosis?

What is a stem cell?

First, let’s investigate what exactly IS a stem cell. There are several things that define a stem cell. One is they are capable of developing into multiple different types of specialized cells. Which means they can become any type of cell in the body, also why doctors are so interested in them for treatments for illnesses and disorders. Another is they are able to divide to produce more stem cells.  And finally they are capable of creating functional tissue. Stem cells are always found in the body, from early embryonic stages, until adulthood. Depending on the type of stem cell, they can be found in various places in the body:
  • HSCs (haematopoietic stem cells) these are adult stem cells that are found in blood and bone marrow and are able to produce all the cells needed to create blood and the immune system.
  • MSCs (mesenchymal stem cells) these are adult stem cells found in a few places in the body, fat tissue, skin and bone marrow. These cells produce other cells which help other stem cells work properly.
  • NSCs (neural stem cells) these are specialized stem cells that help repair myelin in the brain. These can also be created from other stem cells, particularly MSCs.
  • hESCs (human embryonic stem cells) these are cells derived from embryos. They can produce every other type of cell in the body. There is an issue with the therapeutic use of these however, they have been unfortunately found to cause tumors in some cases.
  • iPSCs (induced pluripotent stem cells) these are cells that have been manipulated from other adult cells to create different types of cells. These also have the issue of causing tumors.
The stem cells that are most used for therapeutic use are HSCs and MSCs. (There have been some treatments that have been studied that use embryonic cells as well. Obviously there are ethical issues that go along with these types of cells and treatments.) Once the stem cells are removed, they are cultured and then applied to treatment. There are two main categories of treatment that stem cells may provide for multiple sclerosis. Anti-inflammatory therapy and remyelination.

Types of Stem Cell Treatments:

The anti-inflammatory therapy, aHSCT, can be described as “rebooting in the immune system”. It starts with harvesting your own stem cells from bone marrow, which is called mobilization. Then you will undergo high-dose chemo therapy which destroys your current immune system, this process is called immunoablation. Then the stem cells, which have already been cultured, are infused back into the body and a new immune system is born! Unfortunately it’s not that simple. Usually you will need to stay in the hospital for around 2 weeks to make sure you respond well to treatment. But assuming all goes well, you can expect to be functioning somewhat normally within 4-6 months after the treatment has concluded.
Currently there are many studies going on to assess the effectiveness of HSCT. In one such study, 24 patients were followed with the goal of having no disease activity for 3 years post treatment. In 69.6% of the patients studied, there was no new disease activity within those 3 years. Going even further, within 7.5 years, eight patients had shown enough improvement to stop receiving their disability payments and they returned to work. In 13 years post treatment, not one patient had a full relapse, and only one lesion was documented on an MRI scan. However, one patient did die during the treatment due to complications with the chemotherapy that was administered.
Remyelination is another type of stem cell treatment. This approach involves harvesting cells from various parts of your body, often from adipose (fat) tissue. You can also use previously harvested embryonic tissue. The cells are then grown in cultures to promote development of myelin forming cells. The cells are then directly injected into the nervous system to have best access to the brain.

Availability and Side effects:

Currently Stem Cell treatments are not FDA approved. There are several clinics in other countries that administer HSCT, but only a few clinics in the US offer it currently, and only for individuals who meet certain requirements. Usually this is a treatment for people who have had limited improvement with other “conventional” treatments and have significant impairment. However, one way to access stem cell treatments is through clinical trials. There are many going on currently and who are looking for participants. Check in with your doctor to see if this might be a good treatment for you.
This is a very invasive treatment, so there are serious side effects to consider. With HSCT, you will be essentially destroying your immune system, so the risk of infection is high. There is also a chance of having a negative reaction to the chemotherapy that is administered as well, which happened in the trial I referenced and resulted in patient death. This is one of those treatments that you have to weigh the risk to benefit ratio, and determine if it is a good choice for you.
Stem Cell Treatments appear to be very promising. Obviously they come with their risks, but doesn’t any treatment? Hopefully in the future more studies can be done to show their efficacy and it will become an FDA approved course of treatment. Until then, we can look to clinical studies to access this treatment if we choose to do so.
Have you looked into Stem Cell treatments? Have you done it yourself? Let me know!
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References:

I’M ALISSA!

I help women who have also been diagnosed with Multiple Sclerosis make specific and personalized diet, lifestyle & subconscious changes so that they can begin to heal their body, reduce disease symptoms, and return to a life they love.hey there,

follow along on Instagram:

I think 90% of my clients have talked about already feeling the shift to Fall and Winter hardddd.

They are worried about seasonal depression coming back with a vengeance, feeling sad summer is gone and so many other things.

I know when so many feel the same way, you might too.
I know I feel this way too.

I’m working with them to put habits in place NOW that will support them through the winter months.

Here are 2 small shifts we talked about this week:

1. Get sunlight into your eyeballs as soon as you can in the morning.☀️☀️

Ideally this is outside, there will be many science bro’s out there telling you that anything else “doesn’t count” but I say that’s BS.
Yes, the sunlight will have a greater impact if you’re viewing outside, but even if you’re behind a window it will do something.

2. Move your body!! 💃🏃‍♀️

The change in seasons to colder weather makes it super easy to hibernate and move wayyy less than we were in the summer.
I know I’ve been guilty of that this week and it’s showing in my sleep.
But moving our bodies can be so helpful for regulating so many things in our bodies.
Ideally you’re moving in the morning, but again- any time of day will do. 

These are 2 small shifts that can make it easier for your body to transition to, and live with the Winter months.

Let’s crowdsource… what else helps you in winter?? 
I know there are many other things that can!!

I think 90% of my clients have talked about already feeling the shift to Fall and Winter hardddd.

They are worried about seasonal depression coming back with a vengeance, feeling sad summer is gone and so many other things.

I know when so many feel the same way, you might too.
I know I feel this way too.

I’m working with them to put habits in place NOW that will support them through the winter months.

Here are 2 small shifts we talked about this week:

1. Get sunlight into your eyeballs as soon as you can in the morning.☀️☀️

Ideally this is outside, there will be many science bro’s out there telling you that anything else “doesn’t count” but I say that’s BS.
Yes, the sunlight will have a greater impact if you’re viewing outside, but even if you’re behind a window it will do something.

2. Move your body!! 💃🏃‍♀️

The change in seasons to colder weather makes it super easy to hibernate and move wayyy less than we were in the summer.
I know I’ve been guilty of that this week and it’s showing in my sleep.
But moving our bodies can be so helpful for regulating so many things in our bodies.
Ideally you’re moving in the morning, but again- any time of day will do.

These are 2 small shifts that can make it easier for your body to transition to, and live with the Winter months.

Let’s crowdsource… what else helps you in winter??
I know there are many other things that can!!
...

8 4
All the tools that are inside Holistically Healing MS I’ve used myself to decrease my MS symptoms and significantly feel better in my body.

Over the next 8 weeks, let me be your guide on how to make this a reality for yourself.

We start tomorrow at 5:30pm eastern, you coming?

All the tools that are inside Holistically Healing MS I’ve used myself to decrease my MS symptoms and significantly feel better in my body.

Over the next 8 weeks, let me be your guide on how to make this a reality for yourself.

We start tomorrow at 5:30pm eastern, you coming?
...

9 3
I think I’ve said this in every group I’ve run and with every client I meet with.

(A gross oversimplification disclaimer)
But this: 
people pleasing, being all or nothing, perfectionist (I could go on) 

Is (part of) why we got MS.

These patterns we play out each day are the hardest thing to change- and they also keep us with high stress, high MS symptoms and feeling like crap in our bodies.

Changing these patterns takes awareness, focus and support- all of which you get in Holistically Healing MS.

•If you want the ability to say NO when you’d usually just say yes.. (stop overriding yourself)
•If you want to be ok with putting your needs first (cause I know you’re not lol)
•If you want to finally feel like you’re good enough and doing enough (cause you are)

Join us in HHMS. Along with lifestyle strategies, we go process the emotional burden all those patterns have- which helps to move through them.

Comment HHMS below and I’ll send you the link.

I think I’ve said this in every group I’ve run and with every client I meet with.

(A gross oversimplification disclaimer)
But this:
people pleasing, being all or nothing, perfectionist (I could go on)

Is (part of) why we got MS.

These patterns we play out each day are the hardest thing to change- and they also keep us with high stress, high MS symptoms and feeling like crap in our bodies.

Changing these patterns takes awareness, focus and support- all of which you get in Holistically Healing MS.

•If you want the ability to say NO when you’d usually just say yes.. (stop overriding yourself)
•If you want to be ok with putting your needs first (cause I know you’re not lol)
•If you want to finally feel like you’re good enough and doing enough (cause you are)

Join us in HHMS. Along with lifestyle strategies, we go process the emotional burden all those patterns have- which helps to move through them.

Comment HHMS below and I’ll send you the link.
...

28 10
At some point you have to start trusting the things you’re doing will help and stop jumping to a new thing each week.

Giving up gluten one week?
Then dairy the next?
Maybe jumping into an exercise class a week later?

At some point you gotta pick 1-3 things and stick with them long enough to give them time to make changes in your body!!

Not just a day or week either.

Yes change can happen fast, but usually not that fast. You need to stick with things for long enough to see if they’ll help.

Often you give up before it has a chance to shift anything.

If you’ve been bouncing from thing to thing, throwing random things at the wall and hoping they stick, hoping something will move the needle an inch so you feel even a little bit better.. 

My course Holistically Healing MS is for you.

This is the place to find what works for you, to decrease your MS symptoms.

Comment HHMS below and I’ll send you details.

At some point you have to start trusting the things you’re doing will help and stop jumping to a new thing each week.

Giving up gluten one week?
Then dairy the next?
Maybe jumping into an exercise class a week later?

At some point you gotta pick 1-3 things and stick with them long enough to give them time to make changes in your body!!

Not just a day or week either.

Yes change can happen fast, but usually not that fast. You need to stick with things for long enough to see if they’ll help.

Often you give up before it has a chance to shift anything.

If you’ve been bouncing from thing to thing, throwing random things at the wall and hoping they stick, hoping something will move the needle an inch so you feel even a little bit better..

My course Holistically Healing MS is for you.

This is the place to find what works for you, to decrease your MS symptoms.

Comment HHMS below and I’ll send you details.
...

6 2
At one point I wanted:

•To be able to comfortably go on a walk again with my boyfriend (now husband)

•To not feel like an anxious mess every time I thought about the future (and potential disability)

• To not have waves of pain coursing throughout my body 

I don’t want those things anymore,
because I have them all.

No, I’m not totally cured of feeling anxious about the future, and I still have days (like today tbh) where I feel like a load of 💩

The difference is: 
I can manage all the symptoms
and anxiety
and feeling like 💩
better and differently than I did before, using all the tools I have accumulated over the 15(!!) years I’ve lived with MS as a patient and practitioner.

And these are the tools I share with my clients.

And the tools I share with you inside my Holistically Healing MS course.

This course is an 8 week journey into supporting your MS body so that it can begin to heal.

I know you have the same dreams as I did, 
I know because you’ve told me we’ve talked about them 🤩

I want you to have those things too.

Holistically Healing MS waitlist is closing tomorrow, comment HEALING and I’ll add you to the list.

At one point I wanted:

•To be able to comfortably go on a walk again with my boyfriend (now husband)

•To not feel like an anxious mess every time I thought about the future (and potential disability)

• To not have waves of pain coursing throughout my body

I don’t want those things anymore,
because I have them all.

No, I’m not totally cured of feeling anxious about the future, and I still have days (like today tbh) where I feel like a load of 💩

The difference is:
I can manage all the symptoms
and anxiety
and feeling like 💩
better and differently than I did before, using all the tools I have accumulated over the 15(!!) years I’ve lived with MS as a patient and practitioner.

And these are the tools I share with my clients.

And the tools I share with you inside my Holistically Healing MS course.

This course is an 8 week journey into supporting your MS body so that it can begin to heal.

I know you have the same dreams as I did,
I know because you’ve told me we’ve talked about them 🤩

I want you to have those things too.

Holistically Healing MS waitlist is closing tomorrow, comment HEALING and I’ll add you to the list.
...

14 6
I was talking to a client this week and she talked about how mad she was that she has a chronic illness.

How frustrated she was that she has to “manage this dumb disease” and “has to pay attention to everything she does”.

She also went onto say that she really wants to do all the helpful things, but just can’t get out of these stuck and frustrated feelings.

I get it- I definitely remember feeling similar feelings years ago. And I’m sure you’ve been here as well and might still be there at times.

I wanted to share the reframe that really helped her:

I told her, instead of focusing on “managing your disease”,
what if you thought about how you can set your future self up for feeling better/success/health.

Take the disease totally out of it.
What is 1 thing you can do to help your future self today?

She paused for a moment and I could almost see the light bulb go off in real time (one of my fav moments lol).

She said: that feels so much better and more doable.

If you’ve also been struggling with frustrated feelings about “managing your disease” these are the types of conversations we’ll have in Holistically Healing MS.

Yes I’ll be sharing about diet strategies, movement to help symptoms and stress management techniques, but we’ll also dive deeper into your feelings about it all.

Over the many years I’ve been working with clients, I’ve discovered that these thoughts, feelings and beliefs you have about yourself and your health are the biggest thing to stand in your way.

And when you have support to work through these feelings, you’re able to feel so much better faster.

Only those on the HHMS waitlist will get the presale price, and the opportunity to join the waitlist is dwindling (waitlist gets access next weekend!).

Comment WAITLIST below and I’ll add you to the list!!

I was talking to a client this week and she talked about how mad she was that she has a chronic illness.

How frustrated she was that she has to “manage this dumb disease” and “has to pay attention to everything she does”.

She also went onto say that she really wants to do all the helpful things, but just can’t get out of these stuck and frustrated feelings.

I get it- I definitely remember feeling similar feelings years ago. And I’m sure you’ve been here as well and might still be there at times.

I wanted to share the reframe that really helped her:

I told her, instead of focusing on “managing your disease”,
what if you thought about how you can set your future self up for feeling better/success/health.

Take the disease totally out of it.
What is 1 thing you can do to help your future self today?

She paused for a moment and I could almost see the light bulb go off in real time (one of my fav moments lol).

She said: that feels so much better and more doable.

If you’ve also been struggling with frustrated feelings about “managing your disease” these are the types of conversations we’ll have in Holistically Healing MS.

Yes I’ll be sharing about diet strategies, movement to help symptoms and stress management techniques, but we’ll also dive deeper into your feelings about it all.

Over the many years I’ve been working with clients, I’ve discovered that these thoughts, feelings and beliefs you have about yourself and your health are the biggest thing to stand in your way.

And when you have support to work through these feelings, you’re able to feel so much better faster.

Only those on the HHMS waitlist will get the presale price, and the opportunity to join the waitlist is dwindling (waitlist gets access next weekend!).

Comment WAITLIST below and I’ll add you to the list!!
...

11 2
My reality has changed a whole bunch over the years.

I started out with only a few symptoms. But I could get through the day.

Until all of a sudden I couldn’t.

All within a few years I went from “fine” to:
Having horrible symptoms, had 3 relapses and found myself with “aggressive MS”

This was not ok with me.

Eventually, I took my life into my own hands and rethought how I did most things.
I realized I had to make some changes, or else idk what else was gonna happen to me.

So I did.

I changed my diet.
I changed how I worked out.
I changed my job in the name of stress management.

This is just the tip of the iceberg.

If you want this transformation for you too (I know it’s possible) I’m launching my signature course: Holistically Healing MS in a few weeks. 

This is the course you need to get started on this path for yourself.

Only the waitlist is gonna get the pre sale price… 
Comment WAITLIST below and I’ll add you to it!!

My reality has changed a whole bunch over the years.

I started out with only a few symptoms. But I could get through the day.

Until all of a sudden I couldn’t.

All within a few years I went from “fine” to:
Having horrible symptoms, had 3 relapses and found myself with “aggressive MS”

This was not ok with me.

Eventually, I took my life into my own hands and rethought how I did most things.
I realized I had to make some changes, or else idk what else was gonna happen to me.

So I did.

I changed my diet.
I changed how I worked out.
I changed my job in the name of stress management.

This is just the tip of the iceberg.

If you want this transformation for you too (I know it’s possible) I’m launching my signature course: Holistically Healing MS in a few weeks.

This is the course you need to get started on this path for yourself.

Only the waitlist is gonna get the pre sale price…
Comment WAITLIST below and I’ll add you to it!!
...

49 9

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